Contact Info
Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf
Fluorescence
Citations 2
"Direct Stopped-flow Fluorescence Polarization Immunoassay Of Abused Drugs And Their Metabolites In Urine"
Clin. Chem.
1994 Volume 40, Issue 8 Pages 1489-1493
Notice (8): Undefined variable: uid [APP/View/Elements/citation.ctp, line 40]Dolores Perez-Bendito, Augustina Gomez-Hens and Abaji GaikwadCode Context?>
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Chem.', 'journal_id' => '0494', 'fadid' => 'CLCH1994V0040P01489', 'year' => '1994', 'volume' => '40', 'issue' => '8', 'startpage' => '1489', 'endpage' => '1493', 'type' => 'Journal Article', 'analytes' => ';0862;0216;0405;', 'matrices' => ';0157;', 'techniques' => ';0269;0263;0046;', 'keywords' => ';0446;0090;0258;', 'abstract' => 'Two solution were prepared for filling the two drive syringes of the stopped-flow module. One contained 10 µL of urine and an appropriate volume of the fluorescein-labelled analyte in buffer in a final volume of 0.5 mL. The other contained an appropriate volume of the antibody in 0.5 mL of buffer. Portions (40 µL) of the two solution were transferred to the mixing chamber at 20 ml/s. The time course of the fluorescence intensity was measured in the two emission channels at 550 nm (excitation at 494 nm). The stopped-flow module was computer-controlled and the initial reaction rate was determined in 5-10 s. 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Chromatogr., 1989, 496, 321) was compared with the Abbott TDx method. The r value between the two methods for digoxin added to drug-free serum was 0.9897 (n = 7). However, serum from digitalized patients showed higher digoxin levels by the TDx method, probably owing to cross-reactivity of metabolites. Cross-reactivity of the TDx method towards endogenous material in the serum of certain patient groups was an even greater problem. The HPLC method (loc. cit.) gave complete resolution of digoxin. The calibration graph for this method was rectilinear for 0.5 to 3.3 ng mL-1 of digoxin in a 3 mL serum sample, with a mean coefficient of variation of 5.6% and a detection limit of 0.5 ng injected.', 'language' => 'English', 'updated' => '2020-12-28 11:25:15', 'sjccheck' => 'Yes', 'sjccheckdate' => '2011-01-17 01:30:25', 'hits' => '0', 'urlcheck' => '2014-10-12 00:40:54', 'urlcheckcode' => 'HTTP/1.1 302 Found', 'pauthor_id' => null, 'pauthor' => 'NA', 'address' => 'Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, V6T 1W5, Canada Read More: http://informahealthcare.com/doi/abs/10.3109/00498259009046879', 'email' => 'NA', 'notes' => null, 'url' => '10.3109/00498259009046879', 'urltype' => 'doi', 'gotpdf' => 'no', 'partial' => 'no', 'notanalyte' => '', 'citation' => ''Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', Xenobiotica, 1990 20(6) 635-643', 'firstchar' => 'C', 'twochars' => 'Co', 'CitationsTechnique' => array( [maximum depth reached] ), 'Analyte' => array( [maximum depth reached] ), 'Matrix' => array( [maximum depth reached] ), 'Keyword' => array( [maximum depth reached] ) ) ) ) $c = array( 'id' => '012062', 'authors' => 'Perez Bendito, D.;Gomez Hens, A.;Gaikwad, A.', 'authorsweb' => 'Dolores Perez-Bendito, Augustina Gomez-Hens and Abaji Gaikwad', 'title' => 'Direct stopped-flow fluorescence polarization immunoassay of abused drugs and their metabolites in urine', 'journal' => 'Clin. 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1-Methyl-2-phenylethylamine, Fenopromin, Mydrial, α-Methylphenethylamine, β-Aminopropylbenzene, dl-Amphetamine, 1-Phenyl-2-propylamine, amfetaminum, Actedron, Adderall, Anorexide, Simpatina, Adipan, Finam, α-Methylbenzeneethaneamine, Protioamphetamine, 3-Phenyl-2-propylamine, 300-62-9, Psychedrine, Elastonon, Amphetamin, β-Phenylisopropylamin, β-Phenylisopropylamine, 1-Phenyl-2-propanamine, 2-Amino-1-phenylpropane, racemic-Desoxynor-ephedrine, Benzeneethanamine, α-methyl-, dl-α-Methylphenethylamine, Norephedrane, Propisamine, Raphetamine, Simpatedrin, Sympatedrine, Allodene, Anorexine, Benzebar, Benzedrine, Benzolone, Isoamyne, Mecodrin, Novydrine, Oktedrin, Ortedrine, Percomon, Phenedrine, Profamina, Rhinalator, Sympamine, Weckamine, Isomyn, (+-)-Benzedrine, α-Methylbenzeneethanamine, Amfetamina [Italian], Anfetamina [Spanish], DL-Amphetamine solution, 1-Phenylpropan-2-amin, β-Aminopropylbenzene, Amfetaminum [INN-Latin], 1-Phenyl-2-amino-propan, Amfetamina [INN-Spanish], α-Methylphenylethylamine, Levoamphetamine, Thyramine, Phenethylamine, α-methyl-, Benzeneethanamine, α-methyl-, (+-)-, β-Aminopropylbenzene (VAN), Desoxynorephedrin, levo-Amphetamine, CHEBI:2679, Fenylo-izopropylaminyl [Polish], Benzeneethanamine, α-methyl-, (+-)-α-Methylphenethylamine, HSDB 3287, 1-Phenyl-2-aminopropane (VAN), β-Phenylisopropylamin [German], (+-)-α-Methylphenylethylamine, KWTSXDURSIMDCE-UHFFFAOYSA-N, (+-)-α-Methylbenzeneethanamine, 1-Phenyl-2-amino-propan [German], EINECS 200-458-3, EINECS 206-096-2, NSC 27159, Fenylo-izopropylaminyl, 60-15-1, Phenethylamine, α-methyl-, (+-)-, AI3-02438, Phenethylamine, α-methyl-, (±)-, Amphetamine Sulfate (2:1), Amfetamina, Anfetamina, Benzeneethanamine, α-methyl-, (±)-, Amfetamin (TN), Amfetamine (INN), component of Amodex, Amphetamine, its salts, optical isomers, and salts of its optical isomers, component of Biphetamine, Amfetamine [INN:BAN], Amphetamine resin complex, AC1L1EYQ, β-Phenylisopropylamin, AMPHETAMINE, (D), CHEMBL405, UNII-CK833KGX7E, β-Phenylisopropylamine, α-Methylphenethylamine, Oprea1_447423, α-Methylphenylethylamine, DivK1c_000991, WLN: ZY1&1R, (S)-α-Phenylethylamine, d-α-Methylphenethylamine, 610240_ALDRICH, C9H13N, WLN: ZY1&1R -D, HMS503G03, KBio1_000991, Phenethylamine, α-methyl-, (+)-α-Methylphenethylamine, 610240_FLUKA, NINDS_000991, Adderal, (+)-α-Methylphenylethylamine, AC1Q5065, NSC27159, NSC73713, α-Methylphenethylamine, d-form, AR-1H6584, NSC170999, Adderall XR, (S)-(+)-β-Phenylisopropylamine, Phenethylamine, α-methyl, (+-)-, 60-13-9 (sulfate (2:1)), DB00182, LS-1148, LS-1428, IDI1_000991, Phenethylamine, d-, (plusmn)-amphetamine, Benzeneethanamine, α-methyl-, (S)-, Noclon (Salt/Mix), Norephedrine, deoxy-, Fenamin (Salt/Mix), Ortenal (Salt/Mix), Zedrine (Salt/Mix), Amphetamine Sulfatereg, Euphodyn (Salt/Mix), Stimulan (Salt/Mix), C07514, D07445, Fabedrine (Salt/Mix), Oraldrina (Salt/Mix), Vapedrine (Salt/Mix), Sympametin (Salt/Mix), Phenethylamine, (+)-, 3-phenylpropan-2-amine, L000864, (±)-Benzedrine, Benzeneethanamine, (S)-, SCHEMBL8858, α-Methylbenzeneethanamine, (±)-Desoxynorephedrine, GTPL4804, α-Methylbenzeneethaneamine, DL-α-Methylphenethylamine, ALPHA-METHYL-BENZENEETHANAMIDE (SEE ALSO DL-AMPHETAMINE SULFATE), AMPHETAMINE (SEE ALSO: D-AMPHETAMINE (51-64-9) & AMPHETAMINE SULFATE (60-13-9)), (+/-)-2-Amino-1-phenylpropane, D/L-AMPHETAMINEHYDROCHLORIDE, BDBM50005246, NSC-27159, NSC-73713, AKOS022196414, (±)-β-Phenylisopropylamine, (±)-α-Methylphenethylamine, Benzeneethanamine, ?-methyl-, (+/-)-, (±)-α-Methylphenylethylamine, AN-23365, KB-50276, KB-219221, FT-0631912, FT-0694835, 3797-EP2275420A1, 3797-EP2295439A1, 3797-EP2298734A2, 3797-EP2298742A1, 3797-EP2298779A1, 3797-EP2305219A1, 3797-EP2305648A1, 3797-EP2305656A1, 3797-EP2308867A2, 3797-EP2308870A2, 3797-EP2311801A1, 3797-EP2311802A1, 3797-EP2311803A1, 3797-EP2314571A2, 3797-EP2371814A1, Benzeneethanamine, α-methyl-, (αS)-', 'total' => '3', 'inchi' => 'InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3', 'inchikey' => 'KWTSXDURSIMDCE-UHFFFAOYSA-N', 'formula' => 'C9H13N', 'oxstate' => 'Zero', 'url' => '', 'charge' => '0', 'class1' => '', 'class2' => '', 'class3' => '', 'class4' => '', 'class5' => '', 'isgroup' => 'no', 'checked' => 'no', 'citation_count' => '0', 'updated' => '2015-12-11 16:36:07', 'first' => 'A', 'nametotal' => 'Amphetamine**3', 'AnalytesCitation' => array( [maximum depth reached] ) ), (int) 2 => array( 'id' => '00405', 'name' => 'Benzoylecgonine', 'iupac_name' => '(1S,3S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid', 'casrn' => '519-09-5', 'synonyms' => 'benzoylecgonine, O-Benzoylecgonine, (-)-Benzoylecgonine, o-Benzoyl-(-)-ecgonine, 519-09-5, Benzoylecgonine hydrate, CHEBI:41001, Benzoylecgonine solution, 3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, Benzoylecogonine, UNII-5353I8I6YS, Ecgonine benzoate, DSSTox_CID_26758, DSSTox_RID_81882, DSSTox_GSID_46758, (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylic acid, CAS-519-09-5, Theracys, Cocaine metabolite, NCGC00168248-01, NCGC00168248-02, AC1L9LQO, Epitope ID:158630, B4147_FLUKA, B4147_SIGMA, B8900_FLUKA, B8900_SIGMA, SCHEMBL116803, CHEMBL1231248, CTK1G9668, Ecgonine, benzoate (6CI,7CI), 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, [1R-(exo,exo)]-, 5353I8I6YS, EINECS 208-263-5, Tox21_112607, Tox21_112853, DB01515, AK115678, (1S,3S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylic acid, 1αH,5αH-Tropane-2β-carboxylic acid, 3β-hydroxy-, benzoate (ester) (8CI), 3-β-hydroxy-1-α-H,-5-α-H-tropane-2-β-carboxylic acid benzoate, 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(benzoyloxy)-8-methyl-, (1R,2R,3S,5S)-, 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, (1R,2R,3S,5S)- (9CI)', 'total' => '3', 'inchi' => 'InChI=1S/C16H19NO4/c1-17-11-7-8-12(17)14(15(18)19)13(9-11)21-16(20)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3,(H,18,19)/t11?,12?,13-,14+/m0/s1', 'inchikey' => 'GVGYEFKIHJTNQZ-RFQIPJPRSA-N', 'formula' => 'C16H19NO4', 'oxstate' => 'Zero', 'url' => '', 'charge' => '0', 'class1' => '', 'class2' => '', 'class3' => '', 'class4' => '', 'class5' => '', 'isgroup' => 'no', 'checked' => 'no', 'citation_count' => '0', 'updated' => '2015-12-11 16:21:31', 'first' => 'B', 'nametotal' => 'Benzoylecgonine**3', 'AnalytesCitation' => array( [maximum depth reached] ) ) ), 'Matrix' => array( (int) 0 => array( 'id' => '0157', 'label' => 'Urine', 'level1' => 'Biological fluid', 'level2' => 'urine', 'level3' => '', 'level4' => '', 'level5' => '', 'synonyms' => '', 'total' => '272', 'url' => '', 'updated' => '2015-12-09 20:50:01', 'name' => 'Biological fluid, urine', 'nametotal' => 'Biological fluid, urine**272', 'first' => 'B', 'CitationsMatrix' => array( [maximum depth reached] ) ) ), 'Keyword' => array( (int) 0 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"Comparison Of Digoxin Analysis By High Performance Liquid Chromatography - Post-column Derivatization And Fluorescence-polarization Immunoassay"
Xenobiotica
1990 Volume 20, Issue 6 Pages 635-643
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$viewFile = '/home/stuchalk/public_html/fad/app/View/Elements/citation.ctp' $dataForView = array( 'data' => array( 'Technique' => array( 'id' => '0263', 'label' => 'Fluorescence', 'level1' => 'Fluorescence', 'level2' => 'polarized', 'level3' => '', 'level4' => '', 'level5' => '', 'synonyms' => '', 'champ' => '', 'total' => '2', 'updated' => '0000-00-00 00:00:00', 'name' => 'Fluorescence, polarized', 'nametotal' => 'Fluorescence, polarized**2', 'first' => 'F' ), 'Citation' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ) ) ), 'c' => array( 'id' => '014611', 'authors' => 'Embree, L.;McErlane, K.M.', 'authorsweb' => 'L. Embree and K. M. McErlane', 'title' => 'Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', 'journal' => 'Xenobiotica', 'journal_id' => '1452', 'fadid' => 'XBIO1990V0020P00635', 'year' => '1990', 'volume' => '20', 'issue' => '6', 'startpage' => '635', 'endpage' => '643', 'type' => 'Journal Article', 'analytes' => ';0797;', 'matrices' => ';0124;', 'techniques' => ';0038;0269;0263;', 'keywords' => ';0339;0058;0109;', 'abstract' => 'The method described previously (J. Chromatogr., 1989, 496, 321) was compared with the Abbott TDx method. The r value between the two methods for digoxin added to drug-free serum was 0.9897 (n = 7). However, serum from digitalized patients showed higher digoxin levels by the TDx method, probably owing to cross-reactivity of metabolites. Cross-reactivity of the TDx method towards endogenous material in the serum of certain patient groups was an even greater problem. The HPLC method (loc. cit.) gave complete resolution of digoxin. The calibration graph for this method was rectilinear for 0.5 to 3.3 ng mL-1 of digoxin in a 3 mL serum sample, with a mean coefficient of variation of 5.6% and a detection limit of 0.5 ng injected.', 'language' => 'English', 'updated' => '2020-12-28 11:25:15', 'sjccheck' => 'Yes', 'sjccheckdate' => '2011-01-17 01:30:25', 'hits' => '0', 'urlcheck' => '2014-10-12 00:40:54', 'urlcheckcode' => 'HTTP/1.1 302 Found', 'pauthor_id' => null, 'pauthor' => 'NA', 'address' => 'Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, V6T 1W5, Canada Read More: http://informahealthcare.com/doi/abs/10.3109/00498259009046879', 'email' => 'NA', 'notes' => null, 'url' => '10.3109/00498259009046879', 'urltype' => 'doi', 'gotpdf' => 'no', 'partial' => 'no', 'notanalyte' => '', 'citation' => ''Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', Xenobiotica, 1990 20(6) 635-643', 'firstchar' => 'C', 'twochars' => 'Co', 'CitationsTechnique' => array( 'id' => '015368', 'citation_id' => '014611', 'technique_id' => '0263' ), 'Analyte' => array( (int) 0 => array( [maximum depth reached] ) ), 'Matrix' => array( (int) 0 => array( [maximum depth reached] ) ), 'Keyword' => array( (int) 0 => array( [maximum depth reached] ), (int) 1 => array( [maximum depth reached] ), (int) 2 => array( [maximum depth reached] ) ) ), 'i' => (int) 1 ) $data = array( 'Technique' => array( 'id' => '0263', 'label' => 'Fluorescence', 'level1' => 'Fluorescence', 'level2' => 'polarized', 'level3' => '', 'level4' => '', 'level5' => '', 'synonyms' => '', 'champ' => '', 'total' => '2', 'updated' => '0000-00-00 00:00:00', 'name' => 'Fluorescence, polarized', 'nametotal' => 'Fluorescence, polarized**2', 'first' => 'F' ), 'Citation' => array( (int) 0 => array( 'id' => '012062', 'authors' => 'Perez Bendito, D.;Gomez Hens, A.;Gaikwad, A.', 'authorsweb' => 'Dolores Perez-Bendito, Augustina Gomez-Hens and Abaji Gaikwad', 'title' => 'Direct stopped-flow fluorescence polarization immunoassay of abused drugs and their metabolites in urine', 'journal' => 'Clin. Chem.', 'journal_id' => '0494', 'fadid' => 'CLCH1994V0040P01489', 'year' => '1994', 'volume' => '40', 'issue' => '8', 'startpage' => '1489', 'endpage' => '1493', 'type' => 'Journal Article', 'analytes' => ';0862;0216;0405;', 'matrices' => ';0157;', 'techniques' => ';0269;0263;0046;', 'keywords' => ';0446;0090;0258;', 'abstract' => 'Two solution were prepared for filling the two drive syringes of the stopped-flow module. One contained 10 µL of urine and an appropriate volume of the fluorescein-labelled analyte in buffer in a final volume of 0.5 mL. The other contained an appropriate volume of the antibody in 0.5 mL of buffer. Portions (40 µL) of the two solution were transferred to the mixing chamber at 20 ml/s. The time course of the fluorescence intensity was measured in the two emission channels at 550 nm (excitation at 494 nm). The stopped-flow module was computer-controlled and the initial reaction rate was determined in 5-10 s. The procedure was exemplified by the determination of amphetamine and of the metabolites benzoylecgonine and 11-nor-Δ8-tetrahydrocannabinol-9-carboxylic acid. Calibration graphs for these three were 20-300, 15-300 and 10^-400 µg/l respectively, with detection limits of 7, 5 and 3 µL/l, 3-12 times lower than by conventional fluorescence polarization immunoassay. The new method was also more precise (RSD of 1.4-3.6%, vs. 2.2-7.4%) and recovery was close to 100%. The correlation between the two methods was excellent (r > 0.99).', 'language' => 'English', 'updated' => '2015-12-19 12:31:37', 'sjccheck' => 'No', 'sjccheckdate' => '0000-00-00 00:00:00', 'hits' => '20', 'urlcheck' => '2014-10-13 14:16:03', 'urlcheckcode' => 'HTTP/1.1 200 OK', 'pauthor_id' => '00281', 'pauthor' => '!Perez Bendito, D.', 'address' => 'pau', 'email' => 'pau', 'notes' => 'Fax 34-57-218606', 'url' => 'www.clinchem.org/content/40/8/1489.full.pdf', 'urltype' => 'pdfurl', 'gotpdf' => 'yes', 'partial' => 'no', 'notanalyte' => '', 'citation' => ''Direct stopped-flow fluorescence polarization immunoassay of abused drugs and their metabolites in urine', Clin. Chem., 1994 40(8) 1489-1493', 'firstchar' => 'D', 'twochars' => 'Di', 'CitationsTechnique' => array( [maximum depth reached] ), 'Analyte' => array( [maximum depth reached] ), 'Matrix' => array( [maximum depth reached] ), 'Keyword' => array( [maximum depth reached] ) ), (int) 1 => array( 'id' => '014611', 'authors' => 'Embree, L.;McErlane, K.M.', 'authorsweb' => 'L. Embree and K. M. McErlane', 'title' => 'Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', 'journal' => 'Xenobiotica', 'journal_id' => '1452', 'fadid' => 'XBIO1990V0020P00635', 'year' => '1990', 'volume' => '20', 'issue' => '6', 'startpage' => '635', 'endpage' => '643', 'type' => 'Journal Article', 'analytes' => ';0797;', 'matrices' => ';0124;', 'techniques' => ';0038;0269;0263;', 'keywords' => ';0339;0058;0109;', 'abstract' => 'The method described previously (J. Chromatogr., 1989, 496, 321) was compared with the Abbott TDx method. The r value between the two methods for digoxin added to drug-free serum was 0.9897 (n = 7). However, serum from digitalized patients showed higher digoxin levels by the TDx method, probably owing to cross-reactivity of metabolites. Cross-reactivity of the TDx method towards endogenous material in the serum of certain patient groups was an even greater problem. The HPLC method (loc. cit.) gave complete resolution of digoxin. The calibration graph for this method was rectilinear for 0.5 to 3.3 ng mL-1 of digoxin in a 3 mL serum sample, with a mean coefficient of variation of 5.6% and a detection limit of 0.5 ng injected.', 'language' => 'English', 'updated' => '2020-12-28 11:25:15', 'sjccheck' => 'Yes', 'sjccheckdate' => '2011-01-17 01:30:25', 'hits' => '0', 'urlcheck' => '2014-10-12 00:40:54', 'urlcheckcode' => 'HTTP/1.1 302 Found', 'pauthor_id' => null, 'pauthor' => 'NA', 'address' => 'Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, V6T 1W5, Canada Read More: http://informahealthcare.com/doi/abs/10.3109/00498259009046879', 'email' => 'NA', 'notes' => null, 'url' => '10.3109/00498259009046879', 'urltype' => 'doi', 'gotpdf' => 'no', 'partial' => 'no', 'notanalyte' => '', 'citation' => ''Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', Xenobiotica, 1990 20(6) 635-643', 'firstchar' => 'C', 'twochars' => 'Co', 'CitationsTechnique' => array( [maximum depth reached] ), 'Analyte' => array( [maximum depth reached] ), 'Matrix' => array( [maximum depth reached] ), 'Keyword' => array( [maximum depth reached] ) ) ) ) $c = array( 'id' => '014611', 'authors' => 'Embree, L.;McErlane, K.M.', 'authorsweb' => 'L. 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The HPLC method (loc. cit.) gave complete resolution of digoxin. The calibration graph for this method was rectilinear for 0.5 to 3.3 ng mL-1 of digoxin in a 3 mL serum sample, with a mean coefficient of variation of 5.6% and a detection limit of 0.5 ng injected.', 'language' => 'English', 'updated' => '2020-12-28 11:25:15', 'sjccheck' => 'Yes', 'sjccheckdate' => '2011-01-17 01:30:25', 'hits' => '0', 'urlcheck' => '2014-10-12 00:40:54', 'urlcheckcode' => 'HTTP/1.1 302 Found', 'pauthor_id' => null, 'pauthor' => 'NA', 'address' => 'Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, V6T 1W5, Canada Read More: http://informahealthcare.com/doi/abs/10.3109/00498259009046879', 'email' => 'NA', 'notes' => null, 'url' => '10.3109/00498259009046879', 'urltype' => 'doi', 'gotpdf' => 'no', 'partial' => 'no', 'notanalyte' => '', 'citation' => ''Comparison of digoxin analysis by high performance liquid chromatography - post-column derivatization and fluorescence-polarization immunoassay', Xenobiotica, 1990 20(6) 635-643', 'firstchar' => 'C', 'twochars' => 'Co', 'CitationsTechnique' => array( 'id' => '015368', 'citation_id' => '014611', 'technique_id' => '0263' ), 'Analyte' => array( (int) 0 => array( 'id' => '00797', 'name' => 'Digoxin', 'iupac_name' => '3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one', 'casrn' => '20830-75-5', 'synonyms' => '3β-((O-2,6-dideoxy-β-D-Ribo-hexopyranosyl-(1rightarrow4)-O-2,6-dideoxy-β-D-Ribo-hexopyranosyl-(1rightarrow4)-2,6-dideoxy-β-D-Ribo-hexopyranosyl)oxy)-12beta,14-dihydroxy-5β-card-20(22)-enolide; (3beta,5beta,12beta)-3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-O-2,6-dideoxy-β-D-ribo-hexapyranosyl-(1->4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; Digoxin; Card-20(22)-enolide, 3-[(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1.fwdarw.4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1.fwdarw.4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3beta,5beta,12beta)-; Lanoxicaps; Lanoxin; SK-Digoxin; ', 'total' => '11', 'inchi' => 'InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1', 'inchikey' => 'LTMHDMANZUZIPE-PUGKRICDSA-N', 'formula' => 'C41H64O14', 'oxstate' => 'Zero', 'url' => '', 'charge' => '0', 'class1' => 'Biological', 'class2' => 'NA', 'class3' => 'NA', 'class4' => 'Molecule', 'class5' => 'Drugs', 'isgroup' => '', 'checked' => 'yes', 'citation_count' => '0', 'updated' => '2015-12-11 16:21:31', 'first' => 'D', 'nametotal' => 'Digoxin**11', 'AnalytesCitation' => array( [maximum depth reached] ) ) ), 'Matrix' => array( (int) 0 => array( 'id' => '0124', 'label' => 'Serum Human', 'level1' => 'Biological fluid', 'level2' => 'blood', 'level3' => 'serum', 'level4' => 'human', 'level5' => '', 'synonyms' => '', 'total' => '103', 'url' => '', 'updated' => '2015-12-08 19:41:10', 'name' => 'Biological fluid, blood, serum, human', 'nametotal' => 'Biological fluid, blood, serum, human**103', 'first' => 'B', 'CitationsMatrix' => array( [maximum depth reached] ) ) ), 'Keyword' => array( (int) 0 => array( 'id' => '0339', 'type' => 'Manifold process', 'keyword' => 'Post-column derivatization', 'newKeyword' => '', 'synonyms' => '', 'fao' => '', 'total' => '646', 'first' => 'P', 'keytotal' => 'Post-column derivatization**646', 'CitationsKeyword' => array( [maximum depth reached] ) ), (int) 1 => array( 'id' => '0058', 'type' => 'Parameter', 'keyword' => 'Calibration', 'newKeyword' => '', 'synonyms' => '', 'fao' => '', 'total' => '308', 'first' => 'C', 'keytotal' => 'Calibration**308', 'CitationsKeyword' => array( [maximum depth reached] ) ), (int) 2 => array( 'id' => '0109', 'type' => 'Detection limit', 'keyword' => 'Detection limit', 'newKeyword' => '', 'synonyms' => '', 'fao' => '', 'total' => '296', 'first' => 'D', 'keytotal' => 'Detection limit**296', 'CitationsKeyword' => array( [maximum depth reached] ) ) ) ) $i = (int) 1 $path = '' $a = '' $url = 'http://dx.doi.org/10.3109/00498259009046879' $aus = 'L. Embree and K. M. McErlane'include - APP/View/Elements/citation.ctp, line 40 View::_evaluate() - CORE/Cake/View/View.php, line 971 View::_render() - CORE/Cake/View/View.php, line 933 View::_renderElement() - CORE/Cake/View/View.php, line 1224 View::element() - CORE/Cake/View/View.php, line 418 include - APP/View/Techniques/view.ctp, line 52 View::_evaluate() - CORE/Cake/View/View.php, line 971 View::_render() - CORE/Cake/View/View.php, line 933 View::render() - CORE/Cake/View/View.php, line 473 Controller::render() - CORE/Cake/Controller/Controller.php, line 968 Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 200 Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 167 [main] - APP/webroot/index.php, line 109