University of North Florida
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Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

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Amperometry

Classification: Amperometry -> reductive

Citations 2

"Reductive Amperometric Determination Of Nitrofurantoin And Acetazolamide At A Sessile Mercury Drop Electrode Using Flow Injection Analysis"
Analyst 1988 Volume 113, Issue 5 Pages 727-730

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Arnold G. Fogg and Ahmed B. Ghawji

Abstract: Nitrofurantoin was determined at -0.70 V vs. SCE in a carrier stream (7 mL min-1) of Britton - Robinson buffer (pH 7.5) containing 1 g L-1 of Na2SO3. The response was rectilinear from 1 to 50 ppm, with a limit of detection of 0.3 ppm and a coefficient of variation (n = 10) of 1.9% for 10 ppm. Acetazolamide was determined at -0.85 V in 0.1 M HCl. The response was rectilinear from 10 to 70 ppm, with a limit of detection of 7 ppm and a coefficient of variation (n = 10) of 2.3% for 10 ppm. In the analysis of aqueous extracts of tablets, the coefficient of variation (n = 3) were <1.0%.
Acetazolamide Drugs Nitrofurantoin Pharmaceutical

"Assessment Of Online Nitration Reactions As A Means Of Determining Nitrate By Reverse Flow Injection With Reductive Amperometric Detection At A Glassy Carbon Electrode"
Analyst 1989 Volume 114, Issue 5 Pages 579-581

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Arnold G. Fogg, S. Paul Scullion and Tony E. Edmonds

Abstract: Five compounds were investigated for use as on-line reagents in concentrated sulphuric acid for the reductive reverse flow injection amperometric determination of nitrate as a nitro derivative at a glassy carbon electrode. The sulphuric acid was diluted rapidly on injecting the reagent solution into a sample carrier stream and therefore the nitration reaction, which generally only takes place at sulphuric acid concentrations of greater than about 70%, had to be rapid. Thiophene-2-carboxylic acid was found to be the most suitable reagent of those studied. The nitration reaction was sufficiently rapid and the first of two reduction steps was at -0.19 V versus SCE (as indicated by linear sweep voltammetry); hence the determination was free from interference by dissolved oxygen. Problems associated with contamination of the electrode surface with reduction product, which caused loss of signal after making repeated injections over an extended period, remained.
Nitrate Reverse