Abstract: A novel flow injection chemiluminescence (CL) method for the determination of ciprofloxacin (CPLX) was reported. The proposed method is based on luminescence produced by KMnO4-Na2 S2O4-Tb3+-CPLX chemiluminescence (CL) system. The effects of some critical experimental conditions were discussed and the optimization of working conditions was investigated. The linear dynamic range is 3.00 x 10^-8 - 9.00 x 10^-7 mol L-1 and the detection limit for CPLX is 4.40 x 10^-9 mol L-1. This method was applied to the determination of CPLX in tablet, urine, and serum samples and the recoveries of real sample analyzes were in the range from 110 ±4 to 104 ±4.

Abstract: Flow-injection analysis-inductively coupled plasma-atomic emission spectrometric (FIA-ICP-AES) method for the determination of 14 rare earth impurities in high-purity yttrium oxide was developed. The effects of some factors including length of transportation tube, volume of sample, exposure time, ICP working parameters, acidity and matrix concentration. were investigated. The dispersion ratio of FIA-ICP-AES method for the given condition was calculated from experimental results. Under optimum conditions the detection limits of different impurities in the method proposed are from 0.25 to 12.5 to mg/g and relative standard deviation in the range of 1.0-2.9%. This method was used for the determination of trace amounts of rare earth impurities in 99-99.99% of yttrium oxide, and their results are in good agreement with those obtained by continuous pneumatic nebulization (CPN)-ICP-AES method. In comparison with the CPN-ICP-AES method, the FIA-ICP-AES is superior in efficiency, precision, influence of acidity and matrix effect, atmosphere of sample used, and permissible concentration of salt. The sensitivity loss in FIA-ICP-AES can be compensated by increasing matrix concentration. in solution This method can be applied to the routine analysis in the rare earth industry. (SFS)