University of North Florida
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Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

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Measurement Science and Technology

  • Publisher: Institute of Physics (IOP)
  • FAD Code: MSST
  • CODEN: MSTCEP
  • ISSN: 0957-0233
  • Abbreviation: Meas. Sci. Technol.
  • DOI Prefix: 10.1088/0957-0233
  • Other Name(s): Journal of Physics E: Scientific Instruments
  • Language: English
  • Comments: Fulltext from 1990 V1

Citations 8

"Development Of The Microchip-based Repeatable Immunoassay System For Clinical Diagnosis"
Meas. Sci. Technol. 2006 Volume 17, Issue 12 Pages 3189-3194
M Kakuta, H Takahashi, S Kazuno, K Murayama, T Ueno and M Tokeshi

Abstract: A microchip-based semi-automated heterogeneous immunoassay was developed wherein a flow injection-like system and repeatable-use gel were employed. Microfluidics used a pump with highly accurate control of flow rate, two injector valves and a microchip. The results of a system suitability test based on dye injection for microfluidics including a thermal lens microscope as a detector were good. A regeneration buffer for antigen-antibody interaction of brain natriuretic peptide (BNP) was found which did not lose binding activity of the antibody on the gels and integration of such an immunoassay scheme into a semi-automated microfluidics system would facilitate repeated-use heterogeneous immunoassay. Good reproducibility of BNP assay was obtained with the selected regeneration buffer. The concentration of BNP in the range of 0.1-100 pg mL -1 (n ? 3) was successfully determined using the system and protocol developed here. © 2006 IOP Publishing Ltd.

"Rh2O3/Ti Electrode Preparation Using Laser Anneal And Its Application To The Determination Of Chemical Oxygen Demand"
Meas. Sci. Technol. 2006 Volume 17, Issue 7 Pages 1995-2000
Jiaqing Li, Luoping Li, Lei Zheng, Yuezhong Xian and Litong Jin

Abstract: The method of preparation of a Rh2O3/Ti electrode by using laser calcination and the characterization by x-ray diffractometer were proposed. The electrode, which could develop organic electrocatalytical oxidation, was employed as an amperometric sensor, together with a flow injection analysis, to measure chemical oxygen demand (COD) of waste water in a speedy way. The measuring principle was based on the current responses on the modified electrode which were proportional to the COD value. Under the optimized experimental condition, the linear range was 50-2000 mg l-1, and the detection limit was 20.0 mg L-1 (S/N ? 3). This method was successfully applied to determine the COD in samples without pretreatment. It was characterized by short analysis time, simplicity, low environmental impact, limited reagent consumption, easy automation and long lifetime of the sensor. Additionally, the COD values obtained by using the proposed method were within 5% of those given by the conventional COD method. © 2006 IOP Publishing Ltd.

"Measurement Of PH Field Of Chemically Reacting Flow In Microfluidic Devices By Laser-induced Fluorescence"
Meas. Sci. Technol. 2004 Volume 15, Issue 5 Pages 955-960
Kyosuke Shinohara, Yasuhiko Sugii, Koji Okamoto, Haruki Madarame, Akihide Hibara, Manabu Tokeshi and Takehiko Kitamori

Abstract: The interaction between chemical reactions and the flow field in microfluidic devices is investigated by a laser-induced fluorescence technique refined for use at microscopic spatial resolution. The pH distribution of chemically reacting flow at a Y-junction in a neutralization reaction in a microfluidic device is successfully visualized at a spatial resolution of 0.89 µm x 0.89 µm.
pH Fluorescence Microfluidic

"A Novel Chemical Image Sensor Consisting Of Integrated Microsensor Array Chips And Pattern Recognition"
Meas. Sci. Technol. 2003 Volume 14, Issue 7 Pages 1040-1046
He Huiqi, Xu Gaixia, Ye Xuesong and Wang Ping

Abstract: A novel chemical image sensor developed for liquid component analysis is proposed in this paper; using it, pH values ranging from 1 to 12 and six kinds of metal ion, namely Cu2+, Fe2+, Fe3+, Ca2+, Zn2+, and Mg2+, can be detected qualitatively and quantitatively. The sensor applies the principles of optical chemistry and microfabrication technology to detect the ion concentrations in the solution, and has the advantages of high sensitivity, reduced contamination, a lower sample volume required, and the capability of detecting several indices at one time. Moreover, three multivariate data analysis methods are suggested in the paper for treating the raw data acquired from the microbeads, and predicting the results. The study demonstrates that the principal component analysis is capable of classifying six kinds of cation with success. Both partial least-squares regression (PLS) and artificial neural networks (ANN) can be used to compute the pH values quantitatively; furthermore, the PLS method has the advantage of requiring fewer iteration steps than the ANN approach.
Copper(II) Iron(2+) Iron(III) Calcium(2+) Zinc(II) Magnesium(II) Partial least squares Neural network Microfluidic

"Submersible Voltammetric Probes For In Situ Real-time Trace Element Measurements In Surface Water, Groundwater And Sediment-water Interface"
Meas. Sci. Technol. 1999 Volume 10, Issue 12 Pages 1202-1213
Tercier-Waeber, M. L.; Buffle, J.; Confalonieri, F.; Riccardi, G.; Sina, A.; Graziottin, F.; Fiaccabrino, G. C.; Koudelka-Hep, M.

Abstract: A summary of the state of the art in the development of two submersible voltammetric probes performed by us to allow continuous, real-time monitoring of trace elements (Cu(II), Pb(II), Cd(II), Zn(II) and Mn(II), Fe(II)) in natural aquatic ecosystems is given. The first one, called the voltammetric in situ (VIP) profiling system, allowed in situ measurements in surface water and groundwater down to 500 m. Its construction required the development of: (i) a gel-integrated, either single or interconnected, array microsensor, (ii) a submersible probe and (iii) hardware, firmware and software for control of the whole system: i.e. data transmission and acquisition, data processing and maintenance operations. The second system, called the sediment-water interface voltammetric in situ profiling (SIVIP) system, has been developed to allow real-time, high spatial resolution trace elements concentration profile measurements at the sediment-water interface. Its construction required the development of: (i) a gel-integrated microsensor array with 64 individually addressable lines, (ii) a voltammetric probe based on powerful double multiplexing system and single potentiostat allowing simultaneous measurements over the 64 sensor lines, and (iii) hardware, firmware and software for control of the whole system. A general description of both systems as well as examples of laboratory characterization and/or field applications are reported.

"Pollution Breakthrough Monitoring Using Optical Sensing And An Artificial Neural Network Decision System"
Meas. Sci. Technol. 1996 Volume 7, Issue 1 Pages 1212-1219
R M Dowdeswell; K G Carr-Brion; W O Boyle

Abstract: The design of a pollution breakthrough monitor for industrial effluents is discussed. This system uses a diode array spectrometer operating in the range 200 - 800 nm to record on-line absorption spectra of flowing industrial effluent. The resulting spectra are then processed by an artificial neural network decision system to determine whether significant changes in the level of pollution have occurred. This is achieved by training the neural network to recognize normal variations in the effluent's absorption spectra and so to respond to abnormal or unusual incidents. Extensive field trials of a prototype system have been conducted at two industrial sites and promising results obtained, indicating that such a system is capable of determining accidental pollution events.

"A Simple Laboratory Procedure For Packaging And Testing Part-fabricated Gas Microsensors"
Meas. Sci. Technol. 1996 Volume 7, Issue 5 Pages 737-741
S Chao

Abstract: Simple schemes for gas microsensor packaging and testing are presented. The packaging procedures were developed for mostly hand operations, without reliance on sophisticated equipment. The compact design and flow-cell features enabled easy configuration for testing in gas streams by flow injection. Automation improved the efficiency of the sampling of gas microsensors and provided a higher compilation rate for the test data.
Sensor Gas phase detection Automation Flowcell

"Detection Of Glucose Via Electrochemiluminescence In A Thin-layer Cell With A Planar Optical Waveguide"
Meas. Sci. Technol. 1995 Volume 6, Issue 9 Pages 1325-1328
J Kremeskotter, R Wilson, D J Schiffrin, B J Luff and J S Wilkinson

Abstract: The possibility was demonstrated of glucose determination using the electrochemiluminescence occurring when luminol is oxidized at an electrode by peroxide generated via oxidation of glucose with glucose oxidase; the light generated by electrochemiluminescence was coupled into a simple planar optical waveguide and collected with a photomultiplier tube for measurement by a photon counter unit. A glass slab coated with indium tin oxide acted as waveguide and electrode, respectively; the electrode was silanized, modified by covalent attachment of glucose oxidase, and mounted onto a thin-layer cell within a flow injection analysis system inside a black box; the solution under test contained 0.1 mM luminol and the electrode was biased at 1 V. This system responded linearly to glucose in the range 0.3-10 mM (correlation coefficient r = 0.9974).
Glucose Chemiluminescence Immobilized enzyme Flowcell