University of North Florida
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Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

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Current Opinion in Biotechnology

  • Publisher: Elsevier
  • FAD Code: CUOP
  • CODEN: CUOBE3
  • ISSN: 0958-1669
  • Abbreviation: Curr. Opin. Biotechnol.
  • DOI Prefix: 10.1016/j.copbio,10.1016/S0958-1669
  • Language: English
  • Comments: Fulltext from 1990 V1

Citations 6

"NMR Tools For Biotechnology"
Curr. Opin. Biotechnol. 1999 Volume 10, Issue 1 Pages 34-41
Paul A Keifer

Abstract: Recent developments in NMR spectroscopy verify that NMR continues to be an exciting area of research. These advances can be placed into three general categories: new hardware; new techniques; and novel applications. The hardware developments include many advances in the area of flow NMR and some new probe designs. The new techniques include several ways to edit the NMR spectra of mixtures without using chromatographic separation. These new NMR tools are now allowing us to analyze complex mixtures, combinatorial-chemistry libraries, bound drugs, unstable compounds, very small samples, and heterogeneous samples.

"Biosensors For Fermentation Control"
Curr. Opin. Biotechnol. 1993 Volume 4, Issue 2 Pages 183-187
Marie-Noëlle Pons

Abstract: Over the past year, biosensor development has been an active area of research. The actual application of biosensors in process monitoring and control is limited to a few cases, mainly as a result of difficulties relating to their long-range stability and their sensitivity to interfering compounds. Steam sterilization is no longer a problem though, as the great majority of sensors are part of flow injection analysis systems.
Fermentation broth Sensor Interferences Process monitoring

"Fermentation Monitoring"
Curr. Opin. Biotechnol. 1992 Volume 3, Issue 1 Pages 40-44
Gokaraju K. Raju and Charles L. Cooney

Abstract: Fermentation monitoring continues to be the focus of much research. Over the last year, important strides were made in improving bioprocess monitoring using NADH fluorescence, viscosity, affinity techniques, enzyme and microbial sensors, calorimetry, flow injection analysis and bioluminescence. Better fermentation monitoring is important for improving understanding, operation, development and control of the process. We expect progress in these areas of research to continue. In addition, we highlight some non-conventional approaches.
Fermentation broth Biotechnology Bioluminescence Review Process monitoring Viscosity

"Biosensors And Flow Injection Analysis"
Curr. Opin. Biotechnol. 1992 Volume 3, Issue 1 Pages 31-39
Chien-Yuan Chen and Isao Karube

Abstract: A review is presented, with 56 references. Applications of the technique, viz. diagnostic analysis, analysis of food and agricultural products, environmental analysis, are discussed. Combining flow injection analysis with a biosensor is a novel biosensing process which has allowed speedy and accurate analysis. Diagnostic analysis is the most important application for biosensing flow injection analysis, but other applications include bioprocess monitoring, analysis of food and agricultural products, as well as environmental analysis. In addition, the analysis of compounds, such as explosives and abused drugs, and monitoring of Salmonella, the microorganism that causes food poisoning, have been reported.
Agricultural Environmental Food Sensor Review Process monitoring

"Fermentation Monitoring"
Curr. Opin. Biotechnol. 1991 Volume 2, Issue 1 Pages 17-22
Bengt Danielsson

Abstract: A review is presented, with 40 references, of analytical methods for fermentation monitoring, with emphasis on HPLC, flow injection analysis and flow calorimetry. The dominating methodologies which are currently being applied to fermentation monitoring are high-performance liquid chromatography and flow injection analysis. The latter technique is generally combined with immobilized enzymes or biosensors. In an unexpectedly large number of studies, direct measurements on fermentation broth for establishing cell activities are made by flow calorimetry.
Calorimetry HPLC Review

"Flow Injection Analysis With Immobilized Reagents"
Curr. Opin. Biotechnol. 1991 Volume 2, Issue 1 Pages 9-16
Elizabeth A. H. Hall

Abstract: Immobilized reagent phase flow injection analysis can be configured as discrete reagent cells upstream of the sensor element or as an integral reagent/transduction system (flow injection analysis-biosensor). The former approach has attracted greater attention because several assays can be assembled with greater versatility in reagent column units employing a single sensor, than can be co-immobilized on the surface of a transducer. A review is presented, with 19 references.
Sensor Immobilized reagent Review