University of North Florida
Browse the Citations
-OR-

Contact Info

Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

View Stuart Chalk's profile on LinkedIn

Resorcinol

  • IUPAC Name: benzene-1,3-diol
  • Molecular Formula: C6H6O2
  • CAS Registry Number: 108-46-3
  • InChI: InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
  • InChI Key: GHMLBKRAJCXXBS-UHFFFAOYSA-N

@ ChemSpider@ NIST@ PubChem

Citations 8

"Simultaneous Determination Of Gallic Acid And Resorcinol Based On An Oscillating Chemical Reaction By The Analyte Pulse Perturbation Technique"
Anal. Chim. Acta 1996 Volume 334, Issue 3 Pages 323-330
Rafael Jiménez-Prieto, Manuel Silva and Dolores Pérez-Bendito*

Abstract: In a continuous-flow stirred-tank reactor at 35°C were placed 1 mL of 1.25 M H2O2, 1 mL of 0.125 M NaSCN, 1 mL of 0.125 M NaOH, 0.25 mL of 3 mM CuSO4, 0.5 mL of 2 M NaCl, and water to 5 mL. Electrodes were inserted, and a peristaltic pump supplied the reactants and kept the volume of the mixture constant. After a steady state for the Cu(II)-catalyzed reaction between peroxide and thiocyanate was achieved, samples containing 0.1-0.5 µmol of gallic acid and 2.5-3.5 µmol of resorcinol were injected. Changes in the oscillation amplitude and period following perturbation were monitored potentiometrically, and the concentration of each component in the mixture was obtained from calibration graphs. Gallic acid/resorcinol ratios of 1:6 to 1:35 were analyzed. For a mixture containing 0.2 µmol of gallic acid and 3 µmol of resorcinol, the RSD were 4.42 and 3.58%, respectively. The throughput was 5 samples per h.
Potentiometry Oscillating chemical reaction Indirect Steady state

"Multi-data Treatment Applied To The Simultaneous Resolution Of Catechol-resorcinol Mixtures By Kinetic Enzymic Processes"
Talanta 1993 Volume 40, Issue 11 Pages 1601-1607
E. Gómez, A. Cladera, J. M. Estela and V. Cerda*,

Abstract: Mixtures of catechol and resorcinol were analyzed by oxidation with H2O2 and peroxidase in a stopped-flow reversed-flow injection system. The FIA manifold merged a stream of analyte solution with 0.03% H2O2 solution and 0.1 M phosphate buffer solution of pH 7 (all flow rates 0.7 ml/min). After passing through a reaction loop (0.5 m x 0.5 mm i.d.) at 35°C, the mixture was merged with a carrier stream (0.7 ml/min) of 0.1 M phosphate buffer solution of pH 7 at 35°C. A 100 µL volume of peroxidase (7.68 µg/ml) was injected into the carrier stream and after 15 s the flow was halted. The reaction was monitored from 250-550 nm at 1 reading/s. The data was processed using DARRAY and MULTI3 computer programs. The calibration graphs of initial reaction rate vs. concentration, prepared using a set of five multiple standards, were linear for 50-150 µM-catechol and 30-180 µM-resorcinol. The sampling frequency was 60/h.
Spectrophotometry Data acquisition Kinetic Computer Reverse Stopped-flow Heated reaction Multicomponent

"Spectrophotometric Determination Of Phenol And Resorcinol By Reaction With P-aminophenol"
Talanta 1994 Volume 41, Issue 4 Pages 547-556
Karim D. Khalaf, Berween A. Hasan, Angel Morales-Rubio and Miguel de la Guardia*,

Abstract: Three methods for the spectrophotometric determination of phenol and resorcinol based on reaction with p-aminophenol (PAP) were developed: (i) a batch procedure, using dissolved O2 as oxidant; (ii) a stopped-flow procedure using KIO4 as oxidant; and (iii) a flow injection procedure using KIO4 as oxidant. Phenol and resorcinol were determined at 626 and 540 nm, respectively, for all methods. For (i), the optimum experimental conditions were 50 µg/ml of PAP and 20 mM NaOH (2 mM NaOH for resorcinol). The linear ranges were 0.7-20 and 0.06-8 µg/ml for phenol and resorcinol, respectively, and the detection limits were 71 and 6 ng/ml. For (ii), a stream of PAP and KIO4 were merged with the NaOH carrier stream and parked for ~45 min in a reaction coil before transfer to detection cell. The optimum concentration of the reagents are given. The linear ranges were 0.6-20 and 0.07-8 µg/ml of phenol and resorcinol, respectively, and the detection limits were 64 and 7.5 ng/ml, respectively. For (iii), the linear ranges were 1-20 and 0.06-8 µg/ml for phenol and resorcinol, respectively, and the detection limits were 0.97 and 6.6 ng/ml.
Spectrophotometry Optimization Stopped-flow Method comparison

"Inline, Titanium Dioxide-catalysed, Ultra-violet Mineralization Of Toxic Aromatic Compounds In The Waste Stream From A Flow Injection Based Resorcinol Analyser"
Analyst 1995 Volume 120, Issue 2 Pages 231-235
Miguel de la Guardia, Karim D. Khalaf, Berween A. Hasan, Angel Morales-Rubio and Vicente Carbonell

Abstract: A clean method for the spectrophotometric determination of resorcinol is described. A stream (0.8 ml/min) of a 50 µg/ml p-aminophenol solution was mixed with a stream (0.8 ml/min) of 0.2 mM KIO4 in a PTFE reaction coil (45 cm x 0.8 mm i.d.). The resulting solution was merged with a carrier stream (0.8 ml/min) of 6 mM NaOH into which the sample or standard resorcinol solution (500 µL) had been injected. The mixture was passed through a PTFE reaction coil (60 cm x 0.8 mm i.d.) and the absorbance was measured at 540 nm. The waste obtained after the detector was mixed with a slurry (0.8 ml/min) of 0.5 g/l of TiO2 in 0.22 M HCl. The mixture was passed through a PTFE reaction coil (6 m x 0.8 mm i.d.) rolled on a UV lamp and was irradiated at 254 nm. A diagram of the manifold used is given. The detection limit was 16 ng/ml of resorcinol. The RSD (n = 4) for 4 µg/ml of resorcinol was 0.6%. The throughput was 60 samples/h. The use of TiO2-catalyzed UV irradiation allowed complete degradation of the toxic products, thus effecting detoxification of the waste.
Spectrophotometry Catalysis Slurry UV reactor Photochemistry

"Liquid Chromatography - Amperometric Detection Of Catechol, Resorcinol, And Hydroquinone With A Copper-based Chemically Modified Electrode"
Electroanalysis 1992 Volume 4, Issue 2 Pages 183-189
Jianxun Zhou, Erkang Wang

Abstract: Directions are given for the preparation of a vitreous-C electrode coated with crystalline CuCl, which was used in the detection cell as the working electrode, together with an Ag - AgCl reference electrode and a Pt counter electrode. The detector was used for both flow injection analysis and HPLC, in both instances with a 10 µL injection of the sample and with 0.05 M phosphate buffer (pH 7) containing 5% of methanol and 25 mM EDTA as carrier or mobile phase. The HPLC was carried out on a column (20 cm x 4 mm) of Nucleosil C18 (7 µm). Reproducible cathodic current peaks were obtained for all three phenols at +0.1 V. However, at other potentials, anodic currents were observed; the potential used could be chosen to give either positive or negative peaks (assisting identification) or peaks of negligibly small height (eliminating interference). At +0.1 V, calibration graphs were rectilinear for 2 to 1000, 5 to 600 and 5 to 800 ng injected for quinol, resorcinol and catechol, respectively, with corresponding detection limits of 1, 3 and 2 ng.
Electrode Electrode Electrode Amperometry Interferences

"Supersensitive Analytical Detection By Voltammetry"
Am. Lab. 1998 Volume 30, Issue 1 Pages 21-25
Sturrock, P.E.;Barringer, G.E.

Abstract: This paper describes an improved instrument (DP90, Groton Technol., Acton, MA), the design of which was based on experience with the DP82. The DP90 can be used in a traditional manner in unstirred bulk solution or in flow streams as detectors for HPLC or FIA. It operates with a commercial PC as a host computer and features a real-time display of operating parameters and acquired data, the unique ability to change parameters repeatedly during an experiment, the capacity to store all data and parameter values, and the capability of compensating background currents on a point-by-point basis during voltammetric sweeps to allow increased gain in the instrument. (SFS)
Voltammetry Sensitivity

"FIA Spectrophotometric Determination Of Resorcinol In Pharmaceutical Formulations"
J. Flow Injection Anal. 1994 Volume 11, Issue 2 Pages 169-182
Bouhsain, Z.;Hasan, B.A.;Khalaf, K.D.;De La Guardia, M.

Abstract: A flow injection analysis-spectrophotometric method has been developed for the determination of resorcinol in pharmaceutical formulations. The method involves a previous clean-up of samples by means of a solvent extraction with CHCl3, the consecutive extraction of resorcinol with water and the reaction with paminophenol in the presence of KI04, being resorcinol determined spectrophotometrically at 540 mn. The method has a limit of detection of 6.6 ng rnl-1 and provides accurate results in the analysis of real samples.
Pharmaceutical Spectrophotometry

"Flow Injection Analysis Of Hydroquinone, Pyrocatechol, Resorcinol And Pyrogallol With Amperometric Detector"
Nippon Kagaku Kaishi 1986 Volume 1986, Issue 1 Pages 43-48
Satake, H.;Kohri, Y.;Ikeda, S.

Abstract: The sample (20 µL) was injected into a carrier stream of water (1.14 mL min-1) that then met an already mixed stream of 40 µM- or 0.1 mM KIO3 and of 0.42 M KBr in 1 M H2SO4 (0.35 mL min-1 each). The resulting decrease in concentration. of IO3- was detected as a decrease in its reduction current at +0.65 V at a platinum electrode (2 cm x 0.5 mm) placed concentrically in the stream vs. a tubular silver electrode (2 cm x 1.2 mm i.d.) through which the stream passes; the construction of the detector is shown diagrammatically. The peak height varied rectilinearly for 50 µM to 1 mM, 50 µM to 1 mM, 4 µM to 0.2 mM and 20 µM to 0.5 mM concentration. of the respective cited analytes, and the coefficient of variation (n = 4) were <0.7, <1.5, <1.2 and <0.7%, respectively.
Amperometry Electrode Electrode