Contact Info
Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf
4-Aminophenol
- IUPAC Name: 4-aminophenol
- Molecular Formula: C6H7NO
- CAS Registry Number: 123-30-8
- InChI: InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
- InChI Key: PLIKAWJENQZMHA-UHFFFAOYSA-N
Citations 1
"Competitive Heterogeneous Enzyme Immunoassay For Theophylline By Flow Injection Analysis With Electrochemical Detection Of P-aminophenol"
Clin. Chem.
1990 Volume 36, Issue 4 Pages 662-665
EP Gil, HT Tang, HB Halsall, WR Heineman and AS Misiego
Abstract:
A competitive enzyme-linked immunoabsorbent assay based on the flow injection amperometric detection of p-aminophenol has been investigated with use of the materials and general procedure of a commercial kit for the determination of theophylline in human serum. The antibody is immobilized on glass beads, and the enzyme label is alkaline phosphatase (EC 3.1.3.1). The high currents generated during the electrochemical detection allowed a rapid (35 min) and simple determination of theophylline throughout its therapeutic range (10-20 mg/L) and also in the subtherapeutic range (detection limit of about 80 µg/L).
Serum Human
Immunoassay
Amperometry
Electrode
Clinical analysis
Glass beads
Immobilized enzyme
Detection limit