University of North Florida
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Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

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Myo-inositol

  • IUPAC Name: cyclohexane-1,2,3,4,5,6-hexol
  • Molecular Formula: C6H12O6
  • CAS Registry Number: 87-89-8
  • InChI: InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H
  • InChI Key: CDAISMWEOUEBRE-UHFFFAOYSA-N

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Citations 2

"Determination Of Myo-inositol In A Flow Injection System With Immobilized Enzyme Reactors And Amperometric Detection"
Anal. Chim. Acta 1988 Volume 206, Issue 1-2 Pages 49-55
Bo Olsson, György Marko-Varga, Lo Gorton, Roger Appelqvist and Gillis Johansson

Abstract: myo-Inositol 2-dehydrogenase, lactate dehydrogenase and lactate oxidase are co-immobilized on porous glass and used in a packed-bed enzyme reactor. The myoinositol(I) in the biological fluid sample reacts to produce an equivalent amount of H2O2, which oxidizes ferrocyanide to ferrocyanide in a second reactor containing immobilized peroxidase. The ferrocyanide is then detected amperometrically at O mV vs. the SCE in a flow-through detector. The system responds rectilinearly to I concentration. from 1 to 300 µM. The max. throughput was 90 samples h-1, and the enzyme reactor was stable for 5 weeks.
Biological fluid Amperometry Controlled pore glass Immobilized enzyme Merging zones

"Nickel Oxide Dispersed In A Graphite/poly(vinyl Chloride) Composite Matrix For An Electrocatalytic Amperometric Sensor For Alditols In Flow Injection Analysis"
Anal. Chim. Acta 1995 Volume 307, Issue 1 Pages 43-48
Tommaso R. I. Cataldi* and Diego Centonze

Abstract: A chemically modified electrode was prepared with 50% NiO, 7% PVC and graphite and packing the mixture into a PTFE cavity (4 mm i.d.). The electrode was used in a FIA system for the amperometric detection of alditols. The wall-jet detection cell also had a Ag/AgCl(3 M KCl) reference electrode and a stainless-steel auxiliary electrode; the working electrode was maintained at +0.5 V. The carrier electrolyte (0.5 ml/min) was 0.1 M NaOH and the sample injection volume was 50 µL. Calibration graphs were linear up to 50 mM alditol (or 25 mM sorbitol) and detection limits were 0.02 M for sorbitol, myo-inositol and xylitol, 0.05 M for dulcitol, 0.08 M for mannitol and 0.1 M for D-arabitol. The RSD for 0.5 mM of analyte were 0.8-1.5% (n = 4-6). The performance of the electrode was stable over 72 h.
Amperometry Electrode Electrode Sensor Catalysis Flowcell