Contact Info
Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf
Laβlol
- IUPAC Name: 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide
- Molecular Formula: C19H24N2O3
- CAS Registry Number: 36894-69-6
- InChI: InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)
- InChI Key: SGUAFYQXFOLMHL-UHFFFAOYSA-N
Citations 1
"Measurement Of Labetalol By High Performance Liquid Chromatography With Electrochemical Detection"
J. Chromatogr. B
1985 Volume 344, Issue 1 Pages 412-415
Joseph Wang, Mojtaba Bonakdar and Balasaheb K. Deshmukh
Abstract:
Urine was diluted with the mobile phase [acetonitrile - 0.05 M K2HPO4 buffer (pH 6; 7:13) containing Na2EDTA (0.2 g l-1)] and subjected to HPLC on a column (25 cm x 4.6 mm) of Biophase ODS (5 µm) with a mobile-phase flow rate of 1 mL min-1 and amperometric detection with a vitreous-carbon electrode at +0.9 to +0.95 V vs. silver - AgCl. The calibration graph was rectilinear for 5 to 30 ng of labetalol(I) and the detection limit was 0.6 ng injected. The coefficient of variation was 5%. The use of electrochemical detection in flow injection analysis for I is discussed.
Urine
HPLC
Electrode