University of North Florida
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Stuart Chalk, Ph.D.
Department of Chemistry
University of North Florida
Phone: 1-904-620-1938
Fax: 1-904-620-3535
Email: schalk@unf.edu
Website: @unf

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Acetazolamide

  • IUPAC Name: N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
  • Molecular Formula: C4H6N4O3S2
  • CAS Registry Number: 59-66-5
  • InChI: InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
  • InChI Key: BZKPWHYZMXOIDC-UHFFFAOYSA-N

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Citations 1

"Reductive Amperometric Determination Of Nitrofurantoin And Acetazolamide At A Sessile Mercury Drop Electrode Using Flow Injection Analysis"
Analyst 1988 Volume 113, Issue 5 Pages 727-730
Arnold G. Fogg and Ahmed B. Ghawji

Abstract: Nitrofurantoin was determined at -0.70 V vs. SCE in a carrier stream (7 mL min-1) of Britton - Robinson buffer (pH 7.5) containing 1 g L-1 of Na2SO3. The response was rectilinear from 1 to 50 ppm, with a limit of detection of 0.3 ppm and a coefficient of variation (n = 10) of 1.9% for 10 ppm. Acetazolamide was determined at -0.85 V in 0.1 M HCl. The response was rectilinear from 10 to 70 ppm, with a limit of detection of 7 ppm and a coefficient of variation (n = 10) of 2.3% for 10 ppm. In the analysis of aqueous extracts of tablets, the coefficient of variation (n = 3) were <1.0%.
Pharmaceutical Amperometry Electrode Polarography